Huisong Adapatsidwa Chilolezo Choyambitsa Patent Yogwirizana ndi Yuxingcao Qinlan Heji

Pa Novembara 3, 2023, Zhejiang Huisong Pharmaceuticals Co., Ltd. Kupangaku kumawulula njira yodziwira kuchuluka kwa ma nucleosides ku Yuxingcao Qinlan Heji Intermediate. Ma nucleosides apakati amaphatikiza uridine ndi guanosine.
1) Konzani yankho loyesa ndi Yuxingcao Qinlan Heji Intermediate. Konzani yankho lolozera pogwiritsa ntchito uridine reference standard ndi guanosine reference standard.
2) Pangani kusanthula kwa chromatography yamadzi pa njira yolumikizira ndi yankho loyesa, ndikukonzekera Waters Atlantis T3 ngati gawo la chromatographic; Gwiritsani ntchito madzi ngati gawo A loyenda ndi acetonitrile ngati gawo la B pagawo la gradient.
3) Lembani chromatogram, kuwerengera ndi malo pachimake kutsatira njira yakunja muyezo kudziwa zili nucleosides mu mayeso njira.
Njirayi, yomwe ili ndi makhalidwe a nthawi yochepa yowunikira, chofunika chochepa cha chida, ndondomeko yosavuta, ndi zotsatira zolondola komanso zodalirika, zimatha kudzaza kusiyana kwa teknoloji yomwe ilipo mu kayendetsedwe kabwino ka mankhwala opangira mankhwala ndi intermediates.